Formulation & Evaluation of Poly-Herbal Tablets For Management of Obesity

Authors

Kunal K Shinde, Bhushan B Gangurde, Gaurav A Nirbhavane, Shubham M Solat
PG Scholars, Department of Quality Assurance, Sanjivani College of Pharmaceutical Education & Research, Kopargoan, Maharashtra, India.
Poonam P Patil, Assistant Professor & HOD
Department of Pharmaceutical Chemistry, Sanjivani College of Pharmaceutical Education & Research, Kopargoan, Maharashtra, India.

Abstract

Obesity is a serious and chronic disease and a risk factor for life-related chronic diseases. Obesity is caused by an imbalance between energy intake (diet) and energy expenditure, as well as lack of knowledge about nutrition and excessive consumption of fatty substances. Causes basic calories, diet, exercise, genetics and medicine. Obesity is considered a major contributor to chronic non-communicable diseases worldwide. Herbs used in the formula are grape seeds (vitis vinifera), millet seeds, fenugreek seeds. The results of this phytochemical test revealed that papaya seed extract contains flavonoid alkaloids, condensed tannin carbohydrates. Content of flavonoids, carbohydrates and polyphenols, alkaloids in grape seed extract. Fenugreek (12.35%), grape (2.1%), papaya (7%) showed highest loss on drying (LOD). Total ash value result is highest by fenugreek (13.25%), grape (5.4%), papaya (11%). Changes in binding and dispersion ratios of different responses to softening, hardness, and fragmentation. Through this study, we concluded that this poly-herbal tablet is very important for the future management of obesity and is safer and more effective than allopathic medicines available in the market.