Development of SphagneticolaTrilobata Flowers Extract Coated Urinary Catheters: Determining Its Antibacterial Activity against Escherichia coli and Staphylococcus aureus

Authors

Bhavadharani, Reshmi Gopalakrishnan
Department of Microbiology, Sri Ramakrishna College of Arts and Science for Women, Coimbatore, TamilNadu-641044, India.

Karkuvelraja R
Microbial Biodiversity and Bioenergy Lab, Department of Microbiology, Bharathidasan University, Tiruchirapalli-620024, India.

Abstract

Urinary catheters are regularly used withinside the elderly for each short- or long-term. The biofilm formation occurs on the catheters and leads to urinary tract infection. The present study focus on the development of Sphagneticolatrilobata coated catheters for the prevention of urinary tract infections (UTI). Bioactive compounds were extracted using methanol and MIC was determined. Biofilm inhibition assay was determined by Fluorescent microscopic analysis. 7.5mg/ml extracts showed 13mm against E. coli and 14mm against S. aureus. The extract-coated catheter showed a significant reduction in biofilms from the fluorescent microscopic analysis. Hence Sphagneticolatrilobataflower extract coated catheters can be used to prevent biofilm colonization and urinary tract infections.