A critical review on Antidiabetic Potential of Herbal plants and its their bioactive components


T. Sivakumar,
Department of Botany, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
Department of Botany, Thiru A. Govindsamy Government Arts College, Tindivanam, Tamil Nadu, India.

B. Deepa,
Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
Dharmapuram Gnanmbigai Govt. Arts College for Women, Mayiladuthurai, Tamil Nadu, India.


The aim of the recent critical review was to investigate the bioactive components, and antidiabetic activity of ten herbal plants extracts. Herbal plant-derived secondary metabolites of qualitative phytochemicals such as alkaloid, terpenoids, flavonoids, steroid, phenol, anthraquinones, saponin, tannin and glycoside. Herbal plants contain a diversity of biological properties beneficial to humans, like as their antioxidant, antimicrobial, antiallergic, anticancer, anti-inflammatory, and antidiabetic activities. Diabetes mellitus is a chronic disease of metabolic disorders in the β-cells of the pancreas with hyperglycemia. Hyperglycemia can be caused by a lack of insulin production by the pancreas (type 1 diabetes) or by insulin resistance (type 2 diabetes). Present diabetes medications focus on controlling blood glucose levels in the vessel and bringing them down to normal levels. Moreover, most modern drugs have many side effects that cause some important medical problems during treatment. Therefore, herbal plants have been used for a long time and play a vital role as alternative medicines. Also, in the last few years, some new bioactive ingredients isolated from herbal plants have indicated the antidiabetic activity better than the oral hypoglycemic agents used in clinical treatment. Herbal medicine has made a good medical practice and shows a bright future in the treatment of diabetes. Hence, this article modern reviews the bioactive compounds and medicinal effects of ten important herbal plants widely used in the treatment of diabetes.