Analysis of phytochemical constituents and bioactivity of infusion and decoction extracts from Pycnoporus cinnabarinus (Jacq) P. Karst: A comparative study

Pycnoporus cinnabarinus is a red-colored polypore fungus that has been used by the aboriginal people of Nepal to treat ear infections of child and also used in wounds. It has a wide variety of essential bioactive components that showed a promising pharmacological effect. Infusion and decoction are two efficient extraction processes that are employed to extract essential bioactive chemical constituents and subjected for the determination of antioxidant and anti-inflammatory properties of P. cinnabarinus. The result has shown that decoction has a significantly higher quantity of chemical constituents than infusion. Therapeutic activities (in-vitro antioxidant and anti- inflammatory) are also found to be higher in decoction than infusion. This study is focused on the comparative study of bioactive components and investigation of bioactive properties of two different extracts from P. cinnabarinus to show how two different water extracts prepared through different heat treatment influences the chemical composition and pharmacological activities.The study may also be helpful in the exploration of bioactive components and therapeutic prospects of the fungus so that it could be incorporated as a natural drug in herbal medicine against oxidative stress and inflammation-associated diseases.