Saif Ali Muttaleb
Wasit University, College of Basic Education, Department of Science, Wasit, Iraq.
Estabraq Al-Wasiti
Al-Nahrain University, College of Medicine, Department of Chemistry and Biochemistry, Baghdad, Iraq.
Fadhil A. Abboudi
Al-Nahrain University, College of Medicine, Department of Internal Medicine, Baghdad, Iraq.
Assessment of Serum Levels of YKL40 in Patients with Ulcerative Colitis
Authors
Abstract
IBD is a recurring chronic intestinal disease classified into two
subtypes: Crohn’s disease (CD) and ulcerative colitis (UC). YKL-40 is
released by macrophages and neutrophils and is a growth factor for
vascular endothelial cells and fibroblasts. Elevated blood concentrations
of YKL-40 are detected in individuals with illnesses defined by
inflammation or continuing fibrosis. The purpose of this study was to
determine the relationship between serum YKL-40 and clinical disease
activity in individuals with ulcerative colitis (UC). Identifying the cause
of the elevation can be considered one of the most important ways to help
the specialist in identifying UC patients prior to endoscopy.