Demographic Investigations of Some Atopic Dermatitis Patientsin Baghdad Iraq

Authors

Zina Muhanad, Mouruj A AlAubydi
Dept. of Biotechnology, college of sciences, University of Baghdad, Iraq.

Abstract

Atopic dermatitis (AD) is severe allergic skin problems, about 50-70% of children are suffered from AD. This disease may subsequently develop asthma. Several causative agents are related directly or indirectly with AD such as environmental, physiological, genetic causes. Therefore, this study is aimed to investigate some etiological aspects and find the correlation among them. Out of 88 atopic dermatitis patients (41 males and 47 females), the results showed relative association between labour type and AD. Blood grouping results revealed that, AB+, A- and O- are recorded low percentages (6.80%,4.50% and 1.10% respectively) comparable with B+ is recorded the highest percentage 35.20%, then O+ is 27.30% and A+ is 25.00%. As well as the results clarified that the age categories showed increasing number of patients in 3-13 years old 68/ 88 (77.30%) than other age categories.Complete blood counting results showed a variable cell counting values, WBC. Lymphocytes are varying significantly between normal 18 (90.00%), 40(51.90%) and high 2(10.00%), 35 (45.50%) for control and patient respectively. While neutrophil is recorded significant decreasing in patients group 49(63.60%) than control 2(10.00%). Whereas platelets counting revealed a significant variation between AD patients (normal and high) 40(51.90%) and 37(48.10%) than control 17(85.00%) and 3(15.00%) respectively. On another hand, Mean platelet volume (MPV) result showed a significant lowering variation is seen in AD patient age category(0-2year) than control subjects. Whilst platelet distribution width (PDW) result shows the (0-2year) age category patients (13.42±2.01) is more than control subjects 10.20. Nevertheless, Platelets to lymphocytes ratio (PLR) elucidated the median PLR value of atopic dermatitis patients (179.58±47.28) was significantly higher than the median PLR value of the control group (136.76±31.80) in the (14-30years) age patients’ category. However, Neutrophil-to-Lymphocyte Ratio (NLR) values showed, no significant variation is recorded except (3-13years) age category value (1.23±0.43) is decreased than control (2.26±0.90).