Saurabh. Male, Dr. Santosh Tarke, Dr. Gitanjali Chavan, Mr. Vishal Sakhare, Mrs. Ashwini Gholkar
Department of Pharmaceutics, SBSPMs College of Pharmacy, Ambajogai, Beed, Maharashtra, India.
DESIGN AND EVALUATION OF RAPID RELEASE LINAGLIPTIN TABLET FOR DIABETES TREATMENT
Authors
Abstract
The main purpose of linagliptin is to treat diabetes. Linagliptin instant-release tablets were created to increase
the medication's bioavailability and suitability for therapeutic use. The quick-release tablet was formulated
employing several polymers through the application of the direct compression technique. Compressibility index,
Hausner ratio, weight of tablet, bulk density, taped density, hardness, friability, disintegration time, and in vitro
dissolution study. According to preliminary research, formulations with F8 had better drug release properties
and were quicker to release. Experimental confirmation of the results was obtained. According to the study's
findings, the Linagliptin instant release pill that was produced showed improved cumulative drug release, which
in turn improved bioavailability.