Detection Some Immune Aspects of Bed Sore in Iraqi Patients

Bedsores are ulcers that occur on the skin that are under pressure from lying in bed, wearing a cast, sitting in a wheelchair for a prolonged time. It can be a serious problem among weak older adults. This study is aimed to estimation some immune parameters that related directly or indirectly with the innate and adaptive immunity in patients suffering from bed sore. The results showed, out of 76 inpatients randomly collected from several hospitals in Baghdad city/Iraq, males are 49 than females27. Also the reasons of bed sores are varies classified under chronic diseases (diabetes mellitus and /or heart diseases), accidental and surgical wounds and malnutrition with dehydration due to severe diarrhea. Estimation of immune parameters 17A (IL-17A), Interferon gamma (IFN-γ), Perforin -1 (PER-1) and Granzyme A (Gzms-A) revealed, all these parameters are varying significantly among different stages of bedsores. While most of these parameters showed varying significances among different age categories. In conclusion, immune parameters do not elevate in serum significantly as results of bedsores, and may increases locally at skin ulcers.