The vitamin B9, abundantly found in food, vitamin supplements and fortified like
products, provided through such supplements and/or the stable form folate, plays
important role in the synthesis of DNA and RNA, principal material of cell nucleus and
metabolism of amino acid for cell division, as a paramount concern of folic acid
deficiency could lead to serious metabolic manifestations like preterm delivery, infant low
birth weight and fetal growth retardation especially in children and women across the
globe, herein the majority of population takes diets with low concentration of vitamins
and minerals; thus the reduced intake of folic acid further causes the elevated
homocysteine level develops pregnancy complications like placental abruption and
preeclampsia lead to low birth weight and gestation period confers poor pregnancy. The
present study includes the systematic review of overview of folic acid, its deficiency
disorders and its role in cell cycle and its metabolism; methods of extraction and
determination of folic acid and the folic acid rich herbal plants overview to find out the
natural remedy in future, if any.
