Oxadiazole is an important heterocyclic compound containing one oxygen and two nitrogen atoms in the five membered
ring. 1,3,4-oxadiazole is a versatile heterocyclic nucleus having novel molecule which attract the medicinal chemist to
search a new therapeutic molecule. The present review summarizes physicochemical properties, various synthetic
procedures and various pharmacological activities of 1,3,4-oxadiazole moiety. 1,3,4-oxadiazole moiety is an important
pharmacophore which plays a major role in the pharmaceutical chemistry and broad range of important biological
activities such as anti-inflammatory, analgesic, ulcerogenic, antimicrobial, antifungal antitubercular, anticonvulsant,
anticancer/antitumor, antiviral, and antihypertensive activities etc. as reported in the literature.
