Spectroscopic Study of Human Saliva Sample by ATR-FTIR Spectroscopy for Detection of Diabetes Mellitus

Authors

Tavishi Singh
Student,Department of Biomedical Engineering, SRM Institute of Science and Technology, Kancheepuram, Tamil Nadu,India.
Dr. S.P. Angeline Kirubha
Assistant Professor,Department of Biomedical Engineering, SRM Institute of Science and Technology, Kancheepuram, Tamil Nadu,India.
Saswati Dhal
Student, Department of Biomedical Engineering, SRM Institute of Science And Technology, Kancheepuram, Tamil Nadu, India.

Abstract

A huge number of individuals overall live with diabetes and a few millions lose their life from it every year. A non-intrusive, easy strategy for glucose testing would profoundly improve consistence and glucose control while lessening difficulties and the overall disease administration costs. To provide accurate, low cost, and continuous glucose monitoring, in this paper we have tried to test for alternative method by ATR-FTIR spectroscopic studies. The study was conducted on fifteen diabetic and ten healthy individual saliva samples. ATR-FTIR was carried out on the samples. For the validation purpose a standard fasting blood glucose measurement was taken. The correlation between blood glucose level and salivary glucose was established using the transmittance percentage. 950-1180 cm-1 is considered as the spectral region of glucose or sugar moieties. A transmittance percentage peak was found at 1045cm-1 for diabetic subject which shifted to 1039cm-1 for non-diabetic subjects.