Background:-The Coronavirus epidemic 2019 (COVID-19) is really a highly infectious sickness that is causing a huge danger to human life throughout the world. The induction of acute cytokine storm and immunosuppressive in COVID- 19 patients causes a rise in cytokines levels in the blood. Furthermore, the full extent of serum protein alterations in COVID-19 patients remains unclear. Patients and methods: -In a cross-sectional study, 80 SARS-CoV-2 virus-infected patients aged 18 to 80 were categorized according to severity of the infection and their serum protein electrophoresis assessment in relation to the severity of Covid-19. Results:-SPE for patients infected with the SARS-CoV-2 virus showed a significant difference in albumin, beta, and gamma and there was no significant relation with the α1 and α2 all in comparison between the subgroups themselves.
Conclusion:-We conclude from the finding: albumin, beta, and gamma fractions showed a decrease in levels In conjunction with disease severity.