The Important of Adiponectin Level in Progression of Primary Knee Osteoarthritis Disease


Abbas Toma Joda
Researcher, Collage of Medicine, Al-Mustansiriya University, Baghdad, Iraq.


Subject: Primary Knee Osteoarthritis (PKOA) is known as degenerative cartilage cell disease in knee joint association with generation various inflammatory responses. This disease is more common in geriatrics and affected by many factors such as obesity and metabolic. Adiponectin is hormones secreted from fatty tissue involve as a mediator in many pathophysiology processes and supports inflammation at the cartilage of the knee joint. The objective of the Study: Role of the Adiponectin concentration level in progression of Primary knee Osteoarthritis. Materials and Methods: This study was done on 60 patients with PKOA disease and 60 healthy persons (control ), the all subjects’ ages within this study were more than 60 years of both genders. After obtained serum, immediately used quantity method (immunoassay) for the measured level of Adiponectin concentration. Results: This study shows elevation of serum Adiponectin concentration level in the PKOA group compared with the healthy control group. Conclusion: This study confirms that serum Adiponectin concentration level can act as support for PKOA disease progression.