Green Chemistry Approach for Synthesis of Some 1,3,4-Oxadiazole Derivatives As Potent Antimalarial Agents

Green chemistry incorporates a new approach to the synthesis, processing and application of chemical substances in such manner as to reduce threats to health and environment. An efficient synthesis for the preparation of novel azole derivatives by using both conventional and microwave method has been devised. The result revealed that microwave assisted technique is efficient, eco-friendly and in-expensive which are giving higher yield and reduces the reaction time significantly. The synthesized compound was characterized by means of spectral data and compound code 1c showed significant antimalarial activity.